1,602
Participants
Start Date
September 22, 2021
Primary Completion Date
June 1, 2025
Study Completion Date
June 1, 2026
Lidocaine 20mg/ml
Patients in the intervention group will receive an IV lidocaine infusion using a dosage regimen of 1.5 mg/kg bolus of a 2% lidocaine solution with induction of general anesthesia followed by a 2.0 mg/kg/hour infusion until the end of surgery (and up to 30 minutes into recovery room).
Placebo
Patients in the control group will receive a placebo bolus and infusion with normal saline (0.9% sodium chloride solution) until the end of surgery (and up to 30 minutes into recovery room).
RECRUITING
Foothills Medical Centre, Calgary
RECRUITING
Sturgeon Community Hospital, Edmonton
RECRUITING
Eastern Health- Health Sciences Centre, St. John's
RECRUITING
IWK, Halifax
RECRUITING
Juravinski Hospital, Hamilton
RECRUITING
North York General Hospital, North York
RECRUITING
The Ottawa Hospital, Ottawa
RECRUITING
Thunder Bay Regional Health Sciences Centre, Thunder Bay
RECRUITING
Humber River Hospital, Toronto
RECRUITING
Mount Sinai Hospital, Toronto
RECRUITING
St. Michael's Hospital, Toronto
RECRUITING
Sunnybrook Health Sciences Centre, Toronto
RECRUITING
University Health Network, Toronto
RECRUITING
Women's College Hospital, Toronto
RECRUITING
Hôpital Maisonneuve-Rosemont, Montreal
RECRUITING
Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife
Canadian Institutes of Health Research (CIHR)
OTHER_GOV
University Health Network, Toronto
OTHER