A Modified Dose of Rabbit Anti-thymocyte Globulin (rATG) in Children and Adults Receiving Treatment to Help Prepare Their Bodies for a Bone Marrow Transplant

P-rATG days (always starting on Day -12 to -10)

"(1375 - 1500cGy\*) Day -9 to -6~\*TBI dose in 125cGy fractions (with lung shielding) and total dose to be determined by treating physician/radiation oncology and is based off age, stage of disease, and anesthesia requirements."

(5mg/kg/day x 2 day) Day -5 to -4

(60mg/kg/day x 2 days) Day -3 to -2

Day +7

Day -9 to -7 doses 2-3 to be adjusted per PK for target cumulative exposure of 65 mg\*h/L

(70mg/m2/day x 2 days) Day -6 to -5

(25mg/m2/day x 5 days) Day -6 to -2