Genomic Analysis of Families With a History of Discordant Cancers

RecruitingOBSERVATIONAL
Enrollment

150

Participants

Timeline

Start Date

November 17, 2020

Primary Completion Date

July 1, 2028

Study Completion Date

July 1, 2028

Conditions
Discordant Cancers
Interventions
GENETIC

WES via Illumina NextSeq 550 sequencing system

Sequencing will be performed on an Illumina sequencing system

DIAGNOSTIC_TEST

Blood Draw

Blood draw will be via any University Hospitals Laboratory site and sent at room temperature via courier to the Center for Human Genetics (CHG) Laboratory

DIAGNOSTIC_TEST

Skin biopsy

Skin samples obtained via 3mm punch biopsy will be suspended in cell culture media prepared per CHG routine and sent via courier to the Center for Human Genetics Laboratory

DIAGNOSTIC_TEST

Saliva Sample

Participant will provide a saliva sample which be shipped to University Hospitals Laborator site at room temperature

Trial Locations (1)

44106

RECRUITING

University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center, Cleveland

All Listed Sponsors
lead

Case Comprehensive Cancer Center

OTHER