Avo In R/R And Previously Untreated MCL

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

53

Participants

Timeline

Start Date

July 2, 2021

Primary Completion Date

December 31, 2025

Study Completion Date

June 1, 2026

Conditions
Mantle Cell LymphomaRefractory Lymphoma
Interventions
DRUG

Acalabrutinib

"Each study drug is given according to a different schedule:~Acalabrutinib: Oral, dosage per protocol, start cycle 1 and beyond according to schedule outlined in protocol"

DRUG

Venetoclax

Venetoclax: oral. daily, dosage per protocol, start cycle 3 and beyond according to schedule outlined in protocol

DRUG

Obinutuzumab

Obinutuzumab: intravenous infusion, dosage per protocol, drug during cycles 2 and beyond according to schedule outlined in protocol

Trial Locations (3)

60637

RECRUITING

University of Chicago Medical Center, Chicago

02215

RECRUITING

Beth Israel Deaconess Medical Center, Boston

RECRUITING

Dana-Farber Cancer Institute, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Roche-Genentech

INDUSTRY

collaborator

AstraZeneca

INDUSTRY

lead

Austin I Kim

OTHER