Effect of Cyclosporine on the Pharmacokinetics (PK) of AT-527 (R07496998)

PHASE1CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

April 18, 2021

Primary Completion Date

May 10, 2021

Study Completion Date

May 10, 2021

Conditions
Healthy Volunteer Study
Interventions
DRUG

AT-527 550 mg + cyclosporine

550 mg AT-527 alone on Day 1 and 550 mg AT-527 plus 600 mg cyclosporine administered simultaneously on Day 7 Other Names: AT-527 is also known as R07496998

DRUG

AT-527 550 mg + cyclosporine

550 mg AT-527 alone on Day 1 and 550 mg AT-527 plus 600 mg cyclosporine administered on Day 7 (with dosing offset by 2 hrs) Other Names: AT-527 is also known as R07496998

Trial Locations (1)

Unknown

Atea Study Site, Montreal

Sponsors
All Listed Sponsors
collaborator

Hoffmann-La Roche

INDUSTRY

lead

Atea Pharmaceuticals, Inc.

INDUSTRY

NCT04849299 - Effect of Cyclosporine on the Pharmacokinetics (PK) of AT-527 (R07496998) | Biotech Hunter | Biotech Hunter