Investigation of Safety and Efficacy of ABP-450 for Migraine Prevention in Adults

PHASE2CompletedINTERVENTIONAL
Enrollment

797

Participants

Timeline

Start Date

March 1, 2021

Primary Completion Date

June 19, 2024

Study Completion Date

August 6, 2024

Conditions
Migraine
Interventions
DRUG

ABP-450

ABP-450 (prabotulinumtoxinA) contains a 900 kDa botulinum toxin type-A complex produced by the bacterium Clostridium botulinum.

DRUG

Placebo

0.9% sodium chloride, sterile, unpreserved, USP/PhEur

Trial Locations (62)

2170

Liverpool Hospital, Liverpool

3004

Alfred Hospital, Melbourne

3124

Emeritus Research, Camberwell

3350

Grampians Health, Ballarat

10003

New York Neurology Associates, New York

14221

Upstate Clinical Research Associates LLC, Williamsville

14226

Dent Neurologic Institute, Amherst

15236

Preferred Primary Care Physicians, Pittsburgh

19107

Thomas Jefferson University, Jefferson Headache Center, Philadelphia

30060

Drug Studies America, Inc, Marietta

30328

NeuroTrials Research Inc. - Clinedge - PPDS, Atlanta

32746

Sandhill Research, LLC, Lake Mary

33016

Quality Research of South Florida, Hialeah

33126

BioMed Research Institute, INC, Miami

33144

Medical Research Center, LLC, Miami

33157

Innovation Medical Research Center, Palmetto Bay

33467

Canvas Clinical Research, Lake Worth

33810

Clinical Research of Central Florida - ClinEdge - PPDS, Winter Haven

34470

Renstar Medical Research, Ocala

37203

Bryant Research Group, Nashville

37421

WR-ClinSearch, Chattanooga

40825

Quest Research Institute - Hunt - PPDS, Farmington Hills

43016

Centricity Research Dublin Multispecialty, Dublin

43054

The Orthopedic Foundation, New Albany

45432

META Medical Research Institute, LLC, Dayton

45459

Dayton Center for Neurological Disorders, Centerville

49201

Henry Ford Allegiance Neurology, Jackson

60607

Cedar Crosse Research Center, Chicago

63303

StudyMetrix Research, LLC, City of Saint Peters

65810

Clinvest Research LLC, Springfield

66211

Kansas Institute of Research, LLC, Overland Park

68114

Quality Clinical Research, Omaha

68128

Barrett Clinic, P.C. - Clinedge - PPDS, La Vista

70043

Crescent City Headache and Neurology Center, Chalmette

70072

Tandem Clinical Research, Marrero

75225

DCT - Baxter LLC dba Discovery Clinical Trials, Dallas

77478

Mercury Clinical Research Incorporated, Sugar Land

80033

Paradigm Clinical Research Centers, Wheat Ridge

80918

Delta Waves LLC - Hunt - PPDS, Colorado Springs

83642

Velocity Clinical Research - Boise - ERN - PPDS, Meridian

84058

Aspen Clinical Research LLC - Clinedge - PPDS, Orem

85018

Elite Clinical Studies, LLC, Phoenix

85032

Arizona Neuroscience Research, Phoenix

85226

MDFirst Research, Chandler

85281

Clinical Research Consortium Arizona, Tempe

87102

Albuquerque Clinical Trials Inc, Albuquerque

89118

Wake Research - CRCN, LLC, Las Vegas

90067

Los Angeles Headache Center, Los Angeles

90806

Collaborative Neuroscience Research, Long Beach

91942

Velocity Research San Diego, La Mesa

92103

Artemis Institute For Clinical Research LLC - San Diego - ClinEdge - PPDS, San Diego

92324

Axiom Research LLC, Colton

92374

Anderson Clinical Research, Redlands

98004

Northwest Clinical Research Center, Bellevue

06905

New England Institute for Neurology and Headache, Stamford

02131

Boston Clinical Trials Inc, Boston

02451

MedVadis Research, Waltham

08009

Hassman Research Institute - ClinEdge - PPDS, Berlin

T4P 1K4

CARe Clinic, Red Deer

B3S 1N2

True North Clinical Research, Halifax

N7T 4X3

Bluewater Clinical Research Group, Sarnia

G1N 4V3

Diex Recherche Québec, Québec

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

PPD Development, LP

INDUSTRY

lead

AEON Biopharma, Inc.

INDUSTRY