NCT04842006View on ClinicalTrials.gov

Systemic Neoadjuvant and Adjuvant Control by Precision Medicine in Rectal Cancer

NARecruitingINTERVENTIONAL
Enrollment

93

Participants

Timeline

Start Date

December 20, 2021

Primary Completion Date

August 31, 2028

Study Completion Date

December 31, 2031

Conditions
Colorectal Cancer
Interventions
DRUG

Total neoadjuvant therapy (TNT)

Short radiotherapy (5X5 Gy) and capecitabine/oxaliplatin

DIAGNOSTIC_TEST

Minimal residual disease (MRD)

Postoperative MRD on circulating cell-free DNA

RADIATION

Long radiation therapy

Long-course 50.4 Gy radiation with capecitabine

Trial Locations (2)

33520

RECRUITING

Tampere University Hospital, Tampere

00029

RECRUITING

Helsinki University Central Hospital, Helsinki

All Listed Sponsors
lead

Helsinki University Central Hospital

OTHER