51
Participants
Start Date
November 11, 2021
Primary Completion Date
June 30, 2028
Study Completion Date
July 31, 2029
Asciminib 40 MG
40 mg by mouth (PO) when used with imatinib.
Asciminib 40 MG Twice Daily
40 mg twice daily when used with nilotinib.
Asciminib 80 MG daily
80 mg daily when used with dasatinib or taken alone.
Imatinib
Maximum dose of 400 mg PO once daily.
Nilotinib
Maximum dose of 300 mg twice daily.
Dasatinib
Maximum dose of 100 mg PO once daily.
RECRUITING
Memorial Sloan Kettering Cancer Center, New York
RECRUITING
The Barbara Ann Karmanos Cancer Institute, Detroit
RECRUITING
Froedtert Hospital & the Medical College of Wisconsin, Milwaukee
RECRUITING
Huntsman Cancer Institute, Salt Lake City
H. Jean Khoury Cure CML Consortium
OTHER
Medical College of Wisconsin
OTHER