Humoral and T-Cell Responses to COVID-19 Vaccination in Multiple Sclerosis Patients Treated With Ocrelizumab Treated With Ocrelizumab or Natalizumab

CompletedOBSERVATIONAL
Enrollment

48

Participants

Timeline

Start Date

March 2, 2021

Primary Completion Date

July 1, 2021

Study Completion Date

July 1, 2021

Conditions
Multiple SclerosisDemyelinating Autoimmune Diseases, CNSAutoimmune Diseases of the Nervous SystemNervous System DiseasesDemyelinating DiseasesAutoimmune DiseasesImmune System DiseasesPathologic Processes
Interventions
DEVICE

Elecsys semi-quantitative Anti-SARS-CoV-2 antibody test

Subjects will receive an Elecsys semi-quantitative Anti-SARS-CoV-2 antibody test within 4 weeks of receiving their first COVID-19 injection. Within 3-4 weeks of receipt of their final COVID-19 vaccine dose, subjects will receive another Elecsys semi-quantitative Anti-SARS-CoV-2 antibody test.

DEVICE

T-Detect COVID T-cell blood test

A select number of subjects will also receive a qualitative SARS-CoV-2 t-cell immunity test, the T-Detect COVID test, within 3-4 weeks of receipt of their final COVID-19 vaccine dose.

Trial Locations (1)

02481

Dragonfly Research, LLC, Wellesley

Sponsors
All Listed Sponsors
lead

Dragonfly Research, LLC

OTHER

NCT04837651 - Humoral and T-Cell Responses to COVID-19 Vaccination in Multiple Sclerosis Patients Treated With Ocrelizumab Treated With Ocrelizumab or Natalizumab | Biotech Hunter | Biotech Hunter