STAND - Study of the AGN1 LOEP SV Kit Compared to PMMA in Patients With Vertebral Compression Fractures

NARecruitingINTERVENTIONAL
Enrollment

408

Participants

Timeline

Start Date

May 31, 2022

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2027

Conditions
Vertebral Compression FractureCompression FractureVertebral Compression
Interventions
DEVICE

Treatment Group: AGN1 LOEP SV Kit

The AGN1 LOEP SV Kit is intended for fixation of pathological fractures of the vertebral body using vertebral augmentation. Following saline lavage to create space, the AGN1 implant material is injected and hardens in situ to augment the fractured vertebral body. The AGN1 implant material is then resorbed and replaced with new bone.

DEVICE

Control Group: PMMA bone cement

High viscosity PMMA bone cement will be used for vertebral augmentation.

Trial Locations (19)

10029

WITHDRAWN

Mt. Sinai, New York

10467

RECRUITING

Montefiore, The Bronx

20037

WITHDRAWN

GW Medical Faculty Associates, Washington D.C.

21401

WITHDRAWN

Anne Arundel Medical Center (AAMC), Annapolis

28374

RECRUITING

Pinehurst Surgical Clinic, Pinehurst

32804

RECRUITING

Orlando Neurosurgery (Conquest Research), Orlando

34994

RECRUITING

Cleveland Clinic Florida, Stuart

35235

RECRUITING

Alabama Clinical Therapeutics, Birmingham

60201

RECRUITING

NorthShore University HealthSystem, Evanston

60564

WITHDRAWN

Duly Health / NextStage Clinical Research, Naperville

60612

RECRUITING

Rush University Medical Center, Chicago

63130

RECRUITING

Washington University St. Louis, St Louis

66160

RECRUITING

University of Kansas Medical Center Research Institute, Inc., Kansas City

67226

WITHDRAWN

Abay Neuroscience Center / NextStage Clinical Research, Wichita

71101

RECRUITING

Louisiana Spine Institute, Shreveport

75093

ACTIVE_NOT_RECRUITING

Texas Back Institute, Plano

85054

WITHDRAWN

Mayo Clinic, Phoenix

85203

RECRUITING

Elite Pain and Spine Institute, Mesa

01805

RECRUITING

Lahey Medical Center, Burlington

All Listed Sponsors
lead

AgNovos Healthcare, LLC

INDUSTRY