Neurocognition in NSCLC Patients Treated With Osimertinib or Osimertinib + WBI

PHASE2RecruitingINTERVENTIONAL
Enrollment

88

Participants

Timeline

Start Date

April 7, 2021

Primary Completion Date

April 1, 2024

Study Completion Date

October 31, 2025

Conditions
Neurocognitive
Interventions
RADIATION

Osimertinib and whole-brain irradiation

Osimertinib at a dose of 80 mg once per day, and WBI

DRUG

Osimertinib

Osimertinib at a dose of 80 mg once per day, until unacceptable adverse events or disease progression occurred. WBI could be given to patients in experimental arm at any time base on investigator's decision after treatment initiated.

Trial Locations (1)

510060

RECRUITING

Department of Medical Oncology, Cancer Center of Sun Yat-Sen University, Guangzhou

All Listed Sponsors
lead

Sun Yat-sen University

OTHER