88
Participants
Start Date
April 7, 2021
Primary Completion Date
April 1, 2024
Study Completion Date
October 31, 2025
Osimertinib and whole-brain irradiation
Osimertinib at a dose of 80 mg once per day, and WBI
Osimertinib
Osimertinib at a dose of 80 mg once per day, until unacceptable adverse events or disease progression occurred. WBI could be given to patients in experimental arm at any time base on investigator's decision after treatment initiated.
RECRUITING
Department of Medical Oncology, Cancer Center of Sun Yat-Sen University, Guangzhou
Sun Yat-sen University
OTHER