NCT04823299View on ClinicalTrials.gov

Randomized Controlled Trial- Ablation Strategy for Paroxysmal Atrial Fibrillation - Trigger and Substrate Guided Wide Area Radiofrequency Ablation Compared to Pulsed Field Ablation Pulmonary Vein Isolation

NANot yet recruitingINTERVENTIONAL
Enrollment

556

Participants

Timeline

Start Date

August 31, 2025

Primary Completion Date

September 30, 2028

Study Completion Date

February 28, 2029

Conditions
Atrial FibrillationCatheter AblationRadiofrequency Catheter Ablation
Interventions
PROCEDURE

Cryoballoon ablation

Cryoballoon pulmonary vein isolation ablation

PROCEDURE

Radiofrequency catheter ablation +EPS guided trigger and substrate ablation

RF based WACA ± electrophysiological testing guided ablation of non-PV triggers of AF and low voltage area ablation

Trial Locations (2)

K1Y 4W7

University of Ottawa Heart Institute, Ottawa

H3G 1A4

McGill University Health Center, Montreal

Sponsors

Collaborators (1)

Abbott
All Listed Sponsors
collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

collaborator

Abbott

INDUSTRY

lead

Ottawa Heart Institute Research Corporation

OTHER

NCT04823299 - Randomized Controlled Trial- Ablation Strategy for Paroxysmal Atrial Fibrillation - Trigger and Substrate Guided Wide Area Radiofrequency Ablation Compared to Pulsed Field Ablation Pulmonary Vein Isolation | Biotech Hunter | Biotech Hunter