Study of Perioperative Chemotherapy Combined With Tislelizumab and Trastuzumab in the Treatment of GC/EGC

PHASE2RecruitingINTERVENTIONAL
Enrollment

67

Participants

Timeline

Start Date

December 1, 2021

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Stomach Cancer
Interventions
DRUG

Tirelizumab

tislelizumab (intravenously, 200 mg on day 1 of every cycle for 4 preoperative and 12 postoperative cycles)

DRUG

Trastuzumab

Trastuzumab(intravenously, 8 mg/kg loading dose, then 6 mg/kg on days 1 of every cycle for 4 preoperative and 12 postoperative cycles)

DRUG

Docetaxel

docetaxel (intravenously, 50 mg/m2 on day 1 of every cycle for 3 preoperative cycles)

DRUG

S1

S1 (orally, 400mg/m2 BID on day 1\~14 of every cycle for 3 preoperative and 3 postoperative cycles )

DRUG

Oxaliplatin

Oxaliplatin(intravenously, 100 mg /m2 on day 1 of every cycle for 3 preoperative cycles ;130mg /m2 on day 1 of every cycle for 3 postoperative cycles.

Trial Locations (1)

Unknown

RECRUITING

The First Affiliated Hospital of Zhengzhou University, Zhengzhou

All Listed Sponsors
lead

The First Affiliated Hospital of Zhengzhou University

OTHER