Hypertonic Saline Injection For Urinary Incontinence

PHASE3CompletedINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

January 1, 2014

Primary Completion Date

April 1, 2018

Study Completion Date

June 1, 2020

Conditions
Urinary Stress Incontinence
Interventions
PROCEDURE

Periurethral injection

Patients were in the lithotomy position for the procedure. After preparation, topical Lidocaine gel was instilled around the meatus and a 16 F probe was attached. The catheter balloon was inflated to localize the bladder neck and to ensure that injections were performed in the correct anatomical plane. Hypertonic saline (10% NaCl) was injected to the alignment of the urethral meatus in the order of 3-6-9-12 hours of the clock (5 cc to each site, totaling 20 cc). Syringes with 27 Gauge (0.40 mm) outer diameter were used to ensure controlled injection. Since the female urethra is about 4 cm in length, the needle was advanced about 3 cm. Due to the possibility of significant pain with hypertonic saline, 2 cc of Lidocaine hydrochloride was added into the solution.

DRUG

Hypertonic (10%) saline

Periurethral hypertonic saline (10%)

Trial Locations (2)

44100

Turgut Ozal University, Malatya

44120

İnonu University, Malatya

All Listed Sponsors
collaborator

Inonu University

OTHER

lead

Turgut Ozal University

OTHER

NCT04812574 - Hypertonic Saline Injection For Urinary Incontinence | Biotech Hunter | Biotech Hunter