(PROSPECTOR) Screening Study Evaluating the Prevalence of the KIT D816V Mutation in Patients With Systemic Mast Cell Activation

CompletedOBSERVATIONAL
Enrollment

379

Participants

Timeline

Start Date

June 29, 2021

Primary Completion Date

March 31, 2023

Study Completion Date

March 31, 2023

Conditions
Systemic Mast Cell ActivationKIT D816V Mutation
Interventions
OTHER

Screening

After providing informed consent, relevant medical history data, and blood and buccal swab samples will be collected at a single visit from patients presenting with systemic mast cell activation symptoms

Trial Locations (23)

2650

Antwerp University Hospital UZA, Edegem

4031

University of Basel, Basel

10032

Columbia University Medical Center - Herbert Irving Comprehensive Cancer Center HICCC, New York

12203

Charite Universitatsmedizin Berlin, Berlin

12561

Albert P. Hirdt D.O. P.C., New Paltz

14203

Roswell Park Cancer Center, Buffalo

27705

Duke University: Duke Allergy Asthma Airway Center, Durham

30625

Medizinische Hochschule Hannover, Dept. of Dermatology and Allergy, Hanover

31059

CHU Toulouse, Toulouse

35209

Clinical Research Center of Alabama, Birmingham

37126

Azienda Ospedaliera Universitaria Integrata Verona, Verona

45071

Hospital Virgen del Valle, Toledo

45236

Bernstein Clinical Research Center, LLC, Cincinnati

48105

University of Michigan, Ann Arbor

55905

Mayo Clinic, Rochester

75013

Pitié-Salpêtrière Hospital, Paris

80337

Klinik fuer Dermatologie und Allergologie, München

84100

AOU San Giovanni di Dio e Ruggi d'Aragona University of Salerno, Salerno

92130

Scripps Clinic Carmel Valley, San Diego

02115

Brigham and Women's Hospital, Boston

LE1 5WW

University Hospital of Leicester, Leicester

SE1 9RT

Guy's and St Thomas' NHS Foundation Trust, London

PL6 8DH

University Hospitals Plymouth NHS Trust, Plymouth

All Listed Sponsors
lead

Blueprint Medicines Corporation

INDUSTRY