Study to Evaluate the Safety and Efficacy of Teropavimab and Zinlirvimab in Combination With Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection

PHASE1CompletedINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

April 8, 2021

Primary Completion Date

June 9, 2022

Study Completion Date

October 26, 2023

Conditions
HIV-1 Infection
Interventions
DRUG

Oral Lenacapavir

Tablets administered without regard to food

DRUG

Subcutaneous Lenacapavir

Administered in the abdomen via subcutaneous injections

DRUG

Teropavimab

Administered intravenously

DRUG

Zinlirvimab

Administered intravenously

Trial Locations (23)

10029

Icahn School of Medicine at Mount Sinai-Clinical and Translational Research Center, New York

19104

Perelman Center for Advanced Medicine at the Hospital of the University of Pennsylvania, Philadelphia

20892

National Institutes of Health/Clinical Center, Bethesda

27514

NC TraCS Institute-CTRC; University of North Carolina at Chapel Hill, Chapel Hill

27834

The Brody School of Medicine at East Carolina University, ECU Adult Specialty Care, Greenville

28078

Rosedale Health & Wellness, Huntersville

31201

Mercer University, Department of Internal Medicine, Macon

32803

Orlando Immunology Center, Orlando

33136

University of Miami Miller School of Medicine Schiff Center for Liver Disease, Miami

33407

Triple O Research Institute, P.A, West Palm Beach

34982

Midway Immunology and Research Center, Ft. Pierce

38105

St. Jude Children's Research Hospital, Memphis

46202

Indiana CTSI Clinical Research Center, Indianapolis

48072

Be Well Medical Center, Berkley

77098

The Crofoot Research, INC., Houston

78705

Central Texas Clinical Research, Austin

87505

AXCES Research Group, Santa Fe

90036

Ruane Clinical Research Group Inc., Los Angeles

90069

Mills Clinical Research, Los Angeles

92103

UCSD AntViral Research Center (AVRC), San Diego

95811

One Community Health, Sacramento

98104

Peter Shalit, M.D., Seattle

06510

Yale University; School of Medicine; AIDS Program, New Haven

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Gilead Sciences

INDUSTRY