Buspirone Treatment of Anxiety in Williams Syndrome

PHASE4CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

August 1, 2021

Primary Completion Date

September 11, 2023

Study Completion Date

September 11, 2023

Conditions
Williams SyndromeAnxiety
Interventions
DRUG

Buspirone

All participants in the study will receive open-label treatment with orally administered buspirone for the full duration of the 16-week trial. Buspirone has high affinity for serotonin 5-HT1A and 5-HT2 receptors and moderate affinity for dopamine D2 receptors. It is approved for the management of generalized anxiety disorder in adults.

Trial Locations (1)

02421

Lurie Center for Autism, Lexington

All Listed Sponsors
lead

Massachusetts General Hospital

OTHER

NCT04807517 - Buspirone Treatment of Anxiety in Williams Syndrome | Biotech Hunter | Biotech Hunter