Neoadjuvant Toripalimab or Toripalimab in Combination With Carboplatin and Nab-paclitaxel in Untreated HNSCC (HNSCC-002)

PHASE2RecruitingINTERVENTIONAL
Enrollment

57

Participants

Timeline

Start Date

July 8, 2021

Primary Completion Date

December 1, 2023

Study Completion Date

January 1, 2027

Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
DRUG

Toripalimab, nab-paclitaxel, carboplatin

"Patients receive Toripalimab IV on day 1, nab-paclitaxel IV on day 1 and carboplatin IV on day 1.~Treatment repeats every 21 days for up to 2-4 courses in the absence of disease progression or unacceptable toxicity."

DRUG

Toripalimab

"Patients receive Toripalimab IV on day 1.~Treatment repeats every 21 days for up to 2-4 courses in the absence of disease progression or unacceptable toxicity."

PROCEDURE

Surgical resection

Surgical therapy will be at the discretion of the treating surgeon per standard of care.

Trial Locations (1)

510000

RECRUITING

Sun Yat-sen Memorial Hospital, Guangzhou

All Listed Sponsors
lead

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

OTHER