20
Participants
Start Date
August 25, 2021
Primary Completion Date
September 30, 2022
Study Completion Date
January 31, 2023
Calcitriol
Administration of Calcitrol 0.25mcg/24h for a year in Friedreich's Ataxia patients (n=20)
Blood analysis for frataxin's level measurement
"1. Five blood analysis in Friedreich's Ataxia patients: before starting the treatment, and after fifteen days, 4 months, 8 months and 12 months of the treatment.~2. To validate the Frataxin's levels measurement, a blood analysis will also be done in two kind of controls for every Friedreich's Ataxia patient, only once at the beginning of the trial.~The control groups will be composed by:~* Heterozygous Ataxia's Friedreich controls (a close relative of the patient, either a heterozygous sibling or one of the parents)~* Age- and gender-matched controls (supposedly non-heterozygous)."
Blood analysis for hypercalcemia's control
Five blood analysis in Friedreich's Ataxia patients for monitoring the hypercalcemia risk (with measurement of Calcium, D Vitamin, renal function, albumin, protein, phosphate, sodium and potassium) Before starting the treatment, and after fifteen days, at 4 months, 8 months and 12 months of the treatment.
Hospital Santa Caterina/Parc Martí i Julià, Salt
Institut de Recerca Biomèdica de Lleida
OTHER
Universitat de Lleida
OTHER
Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
OTHER
Berta Alemany
OTHER