fMRI-based Neurofeedback to Relieve Drug-resistant Auditory Hallucinations

NANot yet recruitingINTERVENTIONAL
Enrollment

84

Participants

Timeline

Start Date

December 31, 2022

Primary Completion Date

July 31, 2026

Study Completion Date

July 31, 2026

Conditions
SchizophreniaHallucinations, AuditoryHallucinations, Visual
Interventions
OTHER

Active neurofeedback procedure

Patients will perform 5 fMRI sessions. Four consecutive fMRI runs (1/ day) during which they will continuously receive visual feedback computed from the fMRI signal analyzed with the hallucinations decoder. Patients will be trained to maintain the brain state associated with the no-hallucination state using appropriate coping strategies. A 5th fMRI scan will be performed at 1 month post-treatment.

OTHER

Sham neurofeedback procedure

Patients will perform 5 fMRI sessions. Four consecutive fMRI runs (1/ day) during which they will receive a random feedback and a 5th run at 1 month post-treatment.

All Listed Sponsors
collaborator

National Research Agency, France

OTHER

lead

University Hospital, Lille

OTHER

NCT04798131 - fMRI-based Neurofeedback to Relieve Drug-resistant Auditory Hallucinations | Biotech Hunter | Biotech Hunter