Safety and Efficacy Evaluation of Bosutinib Plus Atezolizumab in Newly Diagnosed Chronic Leukemia Adult Patients

PHASE1/PHASE2TerminatedINTERVENTIONAL
Enrollment

9

Participants

Timeline

Start Date

February 24, 2021

Primary Completion Date

September 24, 2021

Study Completion Date

September 24, 2021

Conditions
Chronic Phase-Chronic Myeloid Leukemia
Interventions
DRUG

Bosutinib 400 MG Monotherapy

One cycle (28 days) only with bosutinib 400 mg/day therapy at the beginning of the trial + 12 cycles with bosutinib 400 mg/day therapy after combined therapy

DRUG

Bosutinib 400 MG + Atezolizumab 840 MG in 14 ML Injection

12 cycles with bosutinib 400 mg/day plus atezolizumab 1680 mg q4w therapy between the monotherapy bosutinib cycles

Trial Locations (2)

28034

Hospital Universitario Ramón y Cajal, Madrid

28046

Hospital Universitario La Paz, Madrid

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Pfizer

INDUSTRY

collaborator

Roche Farma, S.A

INDUSTRY

lead

Fundacion Espanola para la Curacion de la Leucemia Mieloide Cronica

OTHER

NCT04793399 - Safety and Efficacy Evaluation of Bosutinib Plus Atezolizumab in Newly Diagnosed Chronic Leukemia Adult Patients | Biotech Hunter | Biotech Hunter