Molecular Assessment and Profiling of Liver Transplant Recipients

Active, not recruitingOBSERVATIONAL
Enrollment

1,500

Participants

Timeline

Start Date

May 26, 2021

Primary Completion Date

December 31, 2027

Study Completion Date

March 31, 2028

Conditions
Liver TransplantationBiomarkers
Interventions
DEVICE

LiverCare

The LiverCare kits contains Streck tubes and PAX gene tubes, which will be collected at the surveillance schedule outlined above, but also prior to any liver biopsy or DSA measurement. For patients who have a histological diagnosis of allograft rejection who are undergoing treatment, serial monitoring of LiverCare will be performed following the schedule above. All research blood tests will be timed with standard clinical testing to avoid any additional needle sticks.

Trial Locations (26)

10029

Icahn School of Medicine at Mount Sinai, New York

10595

Westchester Medical Center, Valhalla

20007

MedStar Georgetown University Hospital, Washington D.C.

21201

University of Maryland Medical Center, Baltimore

23219

Virginia Commonwealth University, Richmond

27710

Duke University, Durham

28204

Atrium Health, Charlotte

29425

Medical Unversity of South Carolina, Charleston

30309

Piedmont Healthcare, Atlanta

33606

Tampa General Hospital, Tampa

38104

University of Tennessee_Methodist Healthcare, Memphis

45267

University of Cincinnati, Cincinnati

48109

University of Michigan, Ann Arbor

48202

Henry Ford Health System, Detroit

63110

Washington Unversity in St. Louis, St Louis

66160

University of Kansas Medical Center, Kansas City

68198

University of Nebraska Medical Center/ Nebraska Medicine, Omaha

70112

Tulane University, New Orleans

73112

INTEGRIS Baptist Medical Center, Oklahoma City

75203

Methodist Health System, Dallas

77030

Baylor College of Medicine, Houston

84107

Intermountain Medical Center, Murray

90033

Keck Medical Center of USC, Los Angeles

98195

University of Washington, Seattle

02114

Massachusetts General Hospital, Boston

02215

Beth Israel Deaconess Medical Center (BIDMC), Boston

Sponsors

Lead Sponsor

All Listed Sponsors
lead

CareDx

INDUSTRY

NCT04793360 - Molecular Assessment and Profiling of Liver Transplant Recipients | Biotech Hunter | Biotech Hunter