The GUARDIAN Pilot Trial

NARecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

April 27, 2021

Primary Completion Date

December 31, 2025

Study Completion Date

March 30, 2026

Conditions
General Surgery
Interventions
OTHER

Tight pressure management

Norepinephrine or phenylephrine infusion to maintain intraoperative MAP ≥85 mmHg, delayed resumption of chronic antihypertensive medications, and a target ward MAP ≥80 mmHg (tight pressure management)

OTHER

Routine pressure management

Routine intraoperative blood pressure management and immediate restart of antihypertensive medications.

Trial Locations (1)

Unknown

RECRUITING

China Japan Union Hospital of Jilin University, Changchun

All Listed Sponsors
lead

The Cleveland Clinic

OTHER