Evaluating the Safety and Efficacy of Polyethylene Glycol (PEG) Mediated Fusion (PEG Fusion)

PHASE2RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

June 1, 2023

Primary Completion Date

October 1, 2025

Study Completion Date

October 1, 2026

Conditions
Peripheral Nerve Injuries
Interventions
DRUG

NTX-001

• PEG fusion is the application of a polyethylene glycol (PEG) using a combination of sequenced reagents to a freshly performed nerve coaptation, or neurorrhaphy, to allow the axonal membranes of the proximal and distal axonal stumps to fuse back together and re-establish full axonal continuity.

Trial Locations (7)

17403

NOT_YET_RECRUITING

Wellspan Health, York

20889

NOT_YET_RECRUITING

Walter Reed National Military Medical Center, Bethesda

21201

NOT_YET_RECRUITING

University of Maryland Medical Center Shock Trauma Center, Baltimore

21213

RECRUITING

Johns Hopkins University School of Medicine, Baltimore

23219

NOT_YET_RECRUITING

Virginia Commonwealth University Medical Center, Richmond

28207

NOT_YET_RECRUITING

OrthoCarolina, Charlotte

78234

NOT_YET_RECRUITING

San Antonio Military Medical Center (SAMMC), San Antonio

All Listed Sponsors
collaborator

United States Department of Defense

FED

lead

Major Extremity Trauma Research Consortium

OTHER