NCT04788615 - Open Label Randomized Multicenter to Assess Efficacy & Tolerability of Ofatumumab 20mg vs. First Line DMT in RMS | Biotech Hunter

Enrollment

185

Participants

Timeline

Start Date

July 23, 2021

Primary Completion Date

November 11, 2025

Study Completion Date

February 13, 2026

Conditions

Multiple Sclerosis

Interventions

DRUG

Ofatumumab

20mg Subcutaneous injection

DRUG

First line DMT

any one of these based on availability at country given as First line DMT Glatiramer acetate 20mg or 40mg or Interferon 22µg or 0.25mg or Peg-Interferon beta-1a 63µg or 125µg or Teriflunomide 14mg or Dimethyl fumarate 120mg or 240mg or Diroximel fumarate 231mg or 462mg

Trial Locations (41)

10043

Novartis Investigative Site, Orbassano

12101

Novartis Investigative Site, Berlin

13353

Novartis Investigative Site, Berlin

15706

Novartis Investigative Site, Santiago de Compostela

17190

Novartis Investigative Site, Salt

20132

Novartis Investigative Site, Milan

25018

Novartis Investigative Site, Montichiari

26655

Novartis Investigative Site, Westerstede

28009

Novartis Investigative Site, Madrid

28034

Novartis Investigative Site, Madrid

28040

Novartis Investigative Site, Madrid

29010

Novartis Investigative Site, Málaga

30029

Novartis Investigative Site, Nîmes

30120

Novartis Investigative Site, El Palmar

33076

Novartis Investigative Site, Bordeaux

33647

Novartis Investigative Site, Bielefeld

34090

Novartis Investigative Site, Montpellier

35000

Novartis Investigative Site, Rennes

38043

Novartis Investigative Site, Grenoble

41009

Novartis Investigative Site, Seville

44137

Novartis Investigative Site, Dortmund

46026

Novartis Investigative Site, Valencia

48903

Novartis Investigative Site, Barakaldo

50937

Novartis Investigative Site, Cologne

57076

Novartis Investigative Site, Siegen

60590

Novartis Investigative Site, Frankfurt am Main

63003

Novartis Investigative Site, Clermont-Ferrand

64109

Novartis Investigative Site, Bayonne

67000

Novartis Investigative Site, Strasbourg

69120

Novartis Investigative Site, Heidelberg

78303

Novartis Investigative Site, Poissy

80054

Novartis Investigative Site, Amiens

80131

Novartis Investigative Site, Napoli

89073

Novartis Investigative Site, Ulm

94010

Novartis Investigative Site, Créteil

95445

Novartis Investigative Site, Bayreuth

95500

Novartis Investigative Site, Gonesse

06202

Novartis Investigative Site, Nice

00133

Novartis Investigative Site, Roma

00189

Novartis Investigative Site, Roma

08035

Novartis Investigative Site, Barcelona