NCT04782830View on ClinicalTrials.gov

Use of Accelerometer for Quantification of Neurogenic Orthostatic Hypotension Symptoms

NARecruitingINTERVENTIONAL
Enrollment

29

Participants

Timeline

Start Date

February 5, 2021

Primary Completion Date

June 1, 2027

Study Completion Date

October 1, 2027

Conditions
Orthostatic; Hypotension, NeurogenicAutonomic FailurePure Autonomic FailureMultiple System AtrophyOrthostatic; Hypotension, Parkinsonism
Interventions
DEVICE

Accelerometer

A uniaxial accelerometer-based activity monitor (ActivpalTM) will be worn by participants on one of the thighs during the 7 days of the placebo and treatment periods.

DRUG

placebo pill

Placebo pill will be taken for 7 days at the same frequency as their regular treatment with either midodrine or atomoxetine.

DRUG

Midodrine or atomoxetine pill

Either midodrine or atomoxetine at their regular dose.

Trial Locations (1)

37232

RECRUITING

Autonomic Dysfunction Center/ Vanderbilt University Medical Center, Nashville

All Listed Sponsors
lead

Vanderbilt University Medical Center

OTHER