NCT04778904 - First-In-Human Study of ChAdOx1-HBV & MVA-HBV Vaccines (VTP-300) for Chronic HBV | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

December 22, 2020

Primary Completion Date

February 24, 2023

Study Completion Date

February 24, 2023

Conditions

Hepatitis B

Interventions

BIOLOGICAL

ChAdOx1-HBV

Chimpanzee Adenovirus Oxford 1-vectored Hepatitis B virus vaccine

BIOLOGICAL

MVA-HBV

Modified Vaccinia Ankara-vectored Hepatitis B virus vaccine

BIOLOGICAL

Nivolumab

Human immunoglobulin G4 monoclonal antibody

Trial Locations (12)

Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City

Kyungpook National University Hospital, Daegu

Keimyung University Dongsan Hospital, Daegu

Chia-Yi Christian Hospital, Chiayi City

Buddhist Tzu Chi Medical Foundation, Dalin

E-Da Hospital, Kaohsiung City

Pusan National University Hospital, Busan

Yonsei University College of Medicine, Seoul

Asan Medical Centre, Seoul

The Catholic University of Korea Seoul Saint Mary's Hospital, Seoul

Nottingham University Hospitals NHS Trust, Nottingham

King's College Hospital NHS Foundation Trust, London