A Pilot Study on Intermittent Ibrutinib in Patients With Advanced-phase Chronic Lymphocytic Leukemia (CLL)

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

February 23, 2018

Primary Completion Date

April 1, 2023

Study Completion Date

December 1, 2027

Conditions
Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
Interventions
DRUG

Ibrutinib

Ibrutinib will be stopped at inclusion in the and the patient will be followed OFF therapy. At clinical progress, ibrutinib will be restarted (ON period) at the same standard dose as used at inclusion. When the patient achieve at least partial response again, a new OFF period is started, and so on.

Trial Locations (9)

7030

RECRUITING

St Olavs Hospital, Trondheim

17176

RECRUITING

Karolinska University Hospital, Stockholm

791 82

RECRUITING

Falu lasarett, Falun

801 87

RECRUITING

Gävle Hospital, Gävle

222 42

NOT_YET_RECRUITING

Skåne University Hospital, Lund

413 45

NOT_YET_RECRUITING

Sahlgrenska University Hospital, Gothenburg

701 85

RECRUITING

Örebro University Hospital, Örebro

901 85

NOT_YET_RECRUITING

Norrland's University Hospital, Umeå

751 85

RECRUITING

Akademiska hospital, Uppsala

All Listed Sponsors
lead

Jeanette Lundin

OTHER