Chemoradiotherapy Versus Biomarker-Guided Therapy for Elderly and Frail GBM Patients

PHASE2RecruitingINTERVENTIONAL
Enrollment

121

Participants

Timeline

Start Date

July 27, 2022

Primary Completion Date

June 30, 2032

Study Completion Date

June 30, 2032

Conditions
Glioblastoma Multiforme
Interventions
OTHER

Biomarker based treatment (Temozolomide monotherapy or Radiotherapy monotherapy)

Temozolomide or Radiotherapy

COMBINATION_PRODUCT

Chemo-Radiotherapy consisting of 40 Gy in 15 daily fractions with concurrent temozolomide.

Temozolomide will be administered at a dose of 75 mg/m2 daily for a total of 21 days. This will be followed by adjuvant temozolomide (150-200 mg/m2 daily for 5 day

Trial Locations (2)

Unknown

RECRUITING

Tom Baker Cancer Centre, Calgary

T6G 1Z2

RECRUITING

Cross Cancer Institute, Edmonton

All Listed Sponsors
lead

AHS Cancer Control Alberta

OTHER