Terazosin for Dementia With Lewy Bodies

PHASE1/PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

October 31, 2026

Primary Completion Date

October 31, 2028

Study Completion Date

December 31, 2028

Conditions
Dementia With Lewy Bodies
Interventions
DRUG

Terazosin Hydrochloride

In this double blind, randomized, placebo controlled phase I clinical trial, subjects randomized into the Terazosin group will receive Terazosin hydrochloride treatment for 15 weeks. Participants will start at 1mg daily for the first 6 week, then the dosage will be increased to 5mg daily over 3 weeks, and continued for the last 6 weeks.

OTHER

Placebo

In this double blind, randomized, placebo controlled phase I clinical trial, subjects randomized into the control group will receive placebo for 15 weeks.

Trial Locations (1)

52252

University of Iowa, Iowa City

All Listed Sponsors
lead

Qiang Zhang

OTHER