Safety and Tolerability of Abelacimab (MAA868) vs. Rivaroxaban in Patients With Atrial Fibrillation

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

1,287

Participants

Timeline

Start Date

February 2, 2021

Primary Completion Date

February 15, 2024

Study Completion Date

December 29, 2028

Conditions
Atrial Fibrillation (AF)Stroke
Interventions
BIOLOGICAL

Abelacimab

Abelacimab provided as liquid in vial (150 mg/mL)

DRUG

Rivaroxaban

Rivaroxaban 15 mg and 20 mg provided as commercially available film-coated tablets

Trial Locations (92)

116

Anthos Investigative Site, Taipei

404

Anthos Investigative Site, Tiachung

807

Anthos Investigative Site, Kaohsiung City

970

Anthos Investigative Site, Hualien City

1033

Anthos Investigative Site, Budapest

1036

Anthos Investigative Site, Budapest

1122

Anthos Investigative Site, Budapest

1134

Anthos Investigative Site, Budapest

3080

Anthos Investigative Site, Seoul

3722

Anthos Investigative Site, Seoul

4025

Anthos Investigative Site, Debrecen

4400

Anthos Investigative Site (4002), Nyíregyháza

Anthos Investigative Site (4003), Nyíregyháza

5900

Anthos Investigative Site, Orosháza

6500

Anthos Investigative Site, Baja

7400

Anthos Investigative Site, Kaposvár

8000

Anthos Investigative Site, Székesfehérvár

8230

Anthos Investigative Site, Balatonfüred

Anthos Investigative Site, Balatonfüred

10100

Anthos Investigative Site, Prague

11217

Anthos Investigative Site, Taipei

11968

Anthos Investigative Site, Southampton

12601

Anthos Investigative Site, Poughkeepsie

13496

Anthos Investigative Site, Seongnam-si

13620

Anthos Investigative Site, Seongnam-si

17011

Anthos Investigative Site, Camp Hill

20109

Anthos Investigative Site, Manassas

21804

Anthos Investigative Site, Salisbury

22042

Anthos Investigative Site, Falls Church

26058

Anthos Investigative Site, Yilan

28645

Anthos Investigative Site, Lenoir

29001

Anthos Investigative Site, Poděbrady

30024

Anthos Investigative Site, Johns Creek

30071

Anthos Investigative Site, Taipei

32086

Anthos Investigative Site, Saint Augustine

33756

Anthos Investigative Site, Clearwater

33777

Anthos Investigative Site, Largo

34695

Anthos Investigative Site, Safety Harbor

35801

Anthos Investigative Site, Huntsville

36608

Anthos Investigative Site, Mobile

37660

Anthos Investigative Site, Kingsport

42303

Anthos Investigative Site, Owensboro

48912

Anthos Investigative Site, Lansing

49201

Anthos Investigative Site, Seogu

58104

Anthos Investigative Site, Fargo

73135

Anthos Investigative Site, Oklahoma City

77339

Anthos Investigative Site, Kingwood

77375

Anthos Investigative Site, Tomball

06905

Anthos Investigative Site, Stamford

32114-2321

Anthos Investigative Site, Daytona Beach

21229-5222

Anthos Investigative Site, Baltimore

01701

Anthos Investigative Site, Framingham

01830

Anthos Investigative Site, Haverhill

08080

Anthos Investigative Site, Sewell

79761-5133

Anthos Investigative Site, Odessa

N1R 7R1

Anthos Investigative Site, Cambridge

P3B 4H5

Anthos Investigative Site, Greater Sudbury

L1J2K1

Anthos Investigative Site, Oshawa

J4V 2G8

Anthos Investigative Site, Greenfield Park

H1T 3Y7

Anthos Investigative Site, Montreal

250 01

Anthos Investigative Site, Brandýs nad Labem

261 01

Anthos Investigative Site, Příbram

274 01

Anthos Investigative Site, Slaný

353 01

Anthos Investigative Site, Mariánské Lázně

541 01

Anthos Investigative Site, Trutnov

460 01

Anthos Investigative Site, Liberec

Anthos Investigative Site, Liberec

470 01

Anthos Investigative Site, Česká Lípa

530 02

Anthos Investigative Site, Pardubice

110 00

Anthos Investigative Site, Prague

158 00

Anthos Investigative Site, Prague

767 01

Anthos Investigative Site, Kroměříž

769 01

Anthos Investigative Site, Holešov

81-423

Anthos Investigative Site, Gdynia

32-500

Anthos Investigative Site, Chrzanów

31-202

Anthos Investigative Site, Krakow

51-162

Anthos Investigative Site, Wroclaw

58-130

Anthos Investigative Site, Żarów

20-001

Anthos Investigative Site, Lublin

22-400

Anthos Investigative Site, Zamość

09-402

Anthos Investigative Site, Płock

02-097

Anthos Investigative Site, Warsaw

04-628

Anthos Investigative Site, Warsaw

37-700

Anthos Investigative Site, Przemyśl

81-157

Anthos Investigative Site, Gdynia

43-316

Anthos Investigative Site, Bielsko-Biala

41-300

Anthos Investigative Site, Dąbrowa Górnicza

41-710

Anthos Investigative Site, Ruda Śląska

43-100

Anthos Investigative Site, Tychy

82-300

Anthos Investigative Site, Elblag

92-213

Anthos Investigative Site, Lodz

158-710

Anthos Investigative Site, Seoul

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

The TIMI Study Group

OTHER

collaborator

Fortrea

INDUSTRY

lead

Anthos Therapeutics, Inc.

INDUSTRY