Endoprosthesis Metal Toxicity Study

CompletedOBSERVATIONAL
Enrollment

20

Participants

Timeline

Start Date

March 19, 2021

Primary Completion Date

May 1, 2024

Study Completion Date

May 1, 2024

Conditions
Bone TumorCancer of BoneHeart DiseasesCognitive ImpairmentCognitive DeclineChemotherapy EffectMemory Problem
Interventions
BEHAVIORAL

Questionnaires

The patient and an informant will be asked to complete a questionnaire about his or hers current and past physical thinking abilities.

BEHAVIORAL

Interviews

Cognition and memory interviews will take place with the patient.

DIAGNOSTIC_TEST

Blood Test

Three blood draws will occur to assess patients immune response, metal levels, and cardiac health.

DIAGNOSTIC_TEST

Echocardiogram

Each echocardiogram takes about 3 hours and 30 minutes. This test uses sound waves to look at your heart. The person doing the test will press on your chest with a machine to obtain the pictures. The pressure may be uncomfortable. The echocardiogram will involve an image enhancement agent infusion to obtain better images.

Trial Locations (1)

55905

Mayo Clinic, Rochester

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

collaborator

National Institute on Aging (NIA)

NIH

lead

Mayo Clinic

OTHER

NCT04755140 - Endoprosthesis Metal Toxicity Study | Biotech Hunter | Biotech Hunter