NCT04750616View on ClinicalTrials.gov

NAD+ Augmentation in Cardiac Surgery Associated Myocardial Injury Trial

PHASE2RecruitingINTERVENTIONAL
Enrollment

304

Participants

Timeline

Start Date

September 13, 2021

Primary Completion Date

April 30, 2025

Study Completion Date

June 30, 2025

Conditions
Ischemia Reperfusion InjuryMyocardial InjuryAcute Kidney Injury
Interventions
DRUG

Niacinamide

Niacinamide 3 grams on the day of surgery and post-surgical days one and two

DRUG

Placebo

Matched placebo on the day of surgery and post-surgical days one and two

Trial Locations (1)

94115

RECRUITING

Kaiser Permanente San Francisco Medical Center, San Francisco

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

collaborator

Beth Israel Deaconess Medical Center

OTHER

collaborator

Cedars-Sinai Medical Center

OTHER

lead

Kaiser Permanente

OTHER