200
Participants
Start Date
April 14, 2021
Primary Completion Date
March 31, 2025
Study Completion Date
March 31, 2027
Prednisone
1mg/kg/d p.o.which will be tapered after 2 months and discontinued over a 6-12 month period.
Cyclophosphamide
1-2mg/kg/d p.o. with a target accumulated dose of 12g.
Rituximab
1000mg I.V. on D1 and at 6 month. After 6 month, in patients with response but not complete remission, Rituximab could be stopped or repeated with a 6 month-interval (12 month, 18 month, 24 month) until complete remission. Rituximab 1000mg I.V. will be repeated on the 15th day of each Rituximab infusion if CD19+ B cell count\>5/ul.
RECRUITING
Peking Union Medical College Hospital, Beijing
Peking Union Medical College Hospital
OTHER