Trial to Investigate the Safety and Efficacy of Cannabidiol Oral Solution (GWP42003-P; CBD-OS) in Children and Adolescents With Autism Spectrum Disorder

PHASE2CompletedINTERVENTIONAL
Enrollment

103

Participants

Timeline

Start Date

May 31, 2021

Primary Completion Date

December 21, 2023

Study Completion Date

December 21, 2023

Conditions
Autism Spectrum Disorder
Interventions
DRUG

GWP42003-P

GWP42003-P oral solution (100 milligrams per milliliter \[mg/mL\] cannabidiol \[CBD\] in sesame oil with anhydrous ethanol, ethanol \[10% v/v\] sweetener \[sucralose\], and strawberry flavoring), administered twice a day (morning and evening)

DRUG

Placebo

Oral placebo to match GWP42003-P oral solution containing sesame oil with anhydrous ethanol, sweetener (sucralose), strawberry flavoring, and beta carotene, administered twice a day (morning and evening)

Trial Locations (23)

4101

Queensland Children's Hospital, South Brisbane

10312

Richmond Behavioral Associates, Staten Island

19104

Children's Hospital of Philadelphia, Philadelphia

32803

APG Research, LLC, Orlando

40292

University of Louisville, Louisville

68159

Zentralinstitut fuer Seelische Gesundheit, Mannheim

77090

Red Oak Psychiatry Associates, PA, Houston

79104

Klinik fur Psychiatrie, Psychotherapie und Psychosomatik im Kindes und Jugendalter, Freiburg im Breisgau

85006

Southwest Autism Research and Resource Center (SARRRC), Phoenix

90024

UCLA Neuropsychiatric Institute, Los Angeles

92093

UCSD School of Medicine, La Jolla

94143

University of California San Francisco, San Francisco

98105

Seattle Children's Research Institute, Seattle

02115

Boston Children's Hospital, Boston

02421

Massachusetts General Hospital (Lurie Center for Autism), Lexington

03168

Monash Medical Centre, Clayton

L1Z0M1

The Kids Clinic, Ajax

K2G1W2

Center for Pediatric Excellence, Ottawa

08007

Instituto Global de Atencion Integral del Neurodesarrollo (IGAIN), Barcelona

08035

Hospital Universitari Vall d'Hebron, Barcelona

08208

Corporacio Sanitaria Parc Tauli, Sabadell

G128QQ

University of Glasgow Institute of Health and Wellbeing, Glasgow

Unknown

Institute of Psychiatry, King's College London, London

Sponsors
All Listed Sponsors
lead

Jazz Pharmaceuticals

INDUSTRY