NCT04737382 - Osimertinib Resistance in Patients With Non-small-cell Lung Carcinoma That Have Progressed. | Biotech Hunter

Enrollment

200

Participants

Timeline

Start Date

August 22, 2019

Primary Completion Date

August 22, 2024

Study Completion Date

August 22, 2024

Conditions

Non-small-cell Lung Carcinoma

Interventions

DIAGNOSTIC_TEST

biopsy

The formalin fixed material will be processed for molecular analysis in a clinically validated diagnostic pipeline according to ISO 15189 or other acceptable standard

DIAGNOSTIC_TEST

ctDAN analysis

ctDNA analysis will be performed using the AVENIO ctDNA targeted kit according to the guidelines from the manufacturer with respect to isolation, library preparation and bioinformatics analysis.

Trial Locations (6)

1066 CX

RECRUITING

The Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam

Unknown

NOT_YET_RECRUITING

Vrije Universiteit Medisch Centrum, Amsterdam

NOT_YET_RECRUITING

Universitair Medisch Centrum Groningen, Groningen

NOT_YET_RECRUITING

Academisch Ziekenhuis Maastricht, Maastricht

NOT_YET_RECRUITING

Radboud Universitair Medisch Centrum, Nijmegen

NOT_YET_RECRUITING

Erasmus MC, Universitair Medisch Centrum Rotterdam, Rotterdam