A Study of CFI-400945 With or Without Azacitidine in Patients With AML, MDS or CMML

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

April 16, 2021

Primary Completion Date

January 31, 2026

Study Completion Date

January 31, 2026

Conditions
Acute Myeloid LeukemiaMyelodysplastic SyndromesChronic Myelomonocytic LeukemiaAMLMDSCMML
Interventions
DRUG

CFI-400945

The starting dose is 32 mg/day for escalation arms and the recommended starting dose for the expansion arms.

DRUG

Azacitidine

Azacitidine will be given at its labeled dose and schedule

Trial Locations (9)

10021

New York Presbyterian Weill Cornell Medical Center, New York

40207

Norton Cancer Institute - Saint Matthews, Louisville

43210

The Ohio State University Comprehensive Cancer Center, Columbus

77030

The University of Texas MD Anderson Cancer Centre, Houston

91010

City of Hope, Duarte

95817

University of California Davis Comprehensive Cancer Center, Sacramento

T6G2B7

University of Alberta, Edmonton

M5G2C1

Princess Margaret Cancer Center, Toronto

Unknown

Queen Mary Hospital, Hong Kong

All Listed Sponsors
lead

Treadwell Therapeutics, Inc

INDUSTRY