Evaluating the Impact of 18F-FDG-PET-CT on Risk Stratification and Treatment Adaptation for Patients with Muscle Invasive Bladder Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

156

Participants

Timeline

Start Date

April 29, 2021

Primary Completion Date

December 31, 2029

Study Completion Date

May 31, 2030

Conditions
Muscle-Invasive Bladder Carcinoma
Interventions
RADIATION

Metastasis directed therapy (MDT)

Patient receives standard of care therapy with either radical cystectomy with pelvic lymph node dissection or trimodality therapy (consisting of a visible complete TURb and radio chemotherapy). Concurrently, the oligometastasis will be treated with stereotactic body radiotherapy or metastasectomy.

DRUG

Immunotherapy

Patient receives standard of care therapy with either radical cystectomy with pelvic lymph node dissection or trimodality therapy (consisting of a visible complete TURb and radio chemotherapy). Afterwards immunotherapy will be initiated and regular follow up will be performed.

PROCEDURE

Standard of care

Patient receives standard of care therapy with either radical cystectomy with pelvic lymph node dissection or trimodality therapy (consisting of a visible complete TURb and radio chemotherapy). Afterwards regular follow up is performed.

Trial Locations (1)

9000

RECRUITING

Ghent University Hospital, Ghent

All Listed Sponsors
collaborator

Kom Op Tegen Kanker

OTHER

lead

University Hospital, Ghent

OTHER