Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults

PHASE1CompletedINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

January 6, 2021

Primary Completion Date

December 14, 2021

Study Completion Date

December 14, 2021

Conditions
Ebola Virus DiseaseMarburg Virus Disease
Interventions
BIOLOGICAL

cAd3-Marburg

A total of 16 healthy adults will be enrolled and vaccinated with a single dose of vaccine. Group 1 (N = 16) will receive a single injection of cAd3-Marburg at 1 x 10\^11 Particle Units (PU) vaccine.

BIOLOGICAL

cAd3-EBO-S

A total of 16 healthy adults will be enrolled and vaccinated with a single dose of vaccine. Group 2 (N = 16) will receive a single injection of cAd3-EBO-S at 1 x 10\^11 Particle Units (PU) vaccine.

Trial Locations (1)

73104

Oklahoma Blood Institute (OBI), Oklahoma City

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

ICON plc

INDUSTRY

collaborator

Oklahoma Blood Institute

OTHER

lead

Albert B. Sabin Vaccine Institute

OTHER

NCT04723602 - Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults | Biotech Hunter | Biotech Hunter