Impact of Evolocumab as an Additional Lipid-lowering Therapy to Changes in Lipid Core Burden Index of Non-culprit Vulnerable Plaque in Patients Who Underwent Percutaneous Coronary Intervention for the Acute Coronary Syndrome

PHASE4RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

March 1, 2021

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Clinical TrialAcute Coronary Syndrome
Interventions
DRUG

Evolocumab

The maximum dose of combined cholesterol therapy (Statin + Ezetimibe) is prescribed for 2 months, and a cholesterol test is performed in an outpatient clinic to ensure that LDL-Cholesterol \<70mg/dL is met. Patients who do not meet the criteria are randomized to maintain current treatment or receive additional Evolocumab according to randomization.

DEVICE

NIRS IVUS

near-infrared spectroscopy

Trial Locations (1)

Unknown

RECRUITING

Korea University Anam Hospital, Seoul

All Listed Sponsors
lead

Korea University Anam Hospital

OTHER