Potassium Canrenoate in Brain-dead Organ Donors: Randomized Controlled Clinical Trial

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

August 26, 2021

Primary Completion Date

December 6, 2023

Study Completion Date

December 6, 2033

Conditions
Brain-dead Organ Donors
Interventions
DRUG

IV Potassium Canrenoate

"Administration of 200 mg of IV potassium canrenoate (diluted in sodium chloride 0.9%) in brain-dead donors within 10 hours after the diagnosis of brain death and before the departure to the operating room.~Second administration of potassium canrenoate 6 hours after first administration if the patient is not YET admitted IN the operating room"

DRUG

IV Sodium Chloride 0.9 %

"Administration of IV sodium chloride 0.9% (placebo) in brain-dead donors within 10 hours after the diagnosis of brain death is made and before the departure to the operating room.~Second administration of IV sodium chloride 0.9% (placebo) 6 hours after first administration if the patient is not YET admitted IN the operating room."

Trial Locations (1)

54500

CHRU de NANCY, Nancy

All Listed Sponsors
lead

Pr. Nicolas GIRERD

OTHER