Study of CD4-Targeted Chimeric Antigen Receptor T-Cells (CD4- CAR-T) in Subjects With Relapsed or Refractory T-Cell Lymphoma

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

September 13, 2021

Primary Completion Date

December 31, 2023

Study Completion Date

December 31, 2025

Conditions
T-Cell LymphomaPeripheral T-Cell Lymphoma RefractoryCutaneous T-Cell Lymphoma RefractoryCutaneous T-Cell Lymphoma RecurrentPeripheral T-Cell Lymphoma Recurrent
Interventions
BIOLOGICAL

LB1901

LB1901 - an autologous CD4-targeted CAR-T immunotherapy

Trial Locations (4)

53226

Medical College of Wisconsin, Milwaukee

55905

Mayo Clinic, Rochester

77030

MD Anderson Cancer Center, Houston

98195

Fred Hutchinson Cancer Research Center, Seattle

Sponsors
All Listed Sponsors
lead

Legend Biotech USA Inc

INDUSTRY

NCT04712864 - Study of CD4-Targeted Chimeric Antigen Receptor T-Cells (CD4- CAR-T) in Subjects With Relapsed or Refractory T-Cell Lymphoma | Biotech Hunter | Biotech Hunter