A Study to Assess How Itraconazole Affects the Uptake and Elimination of Capivasertib in the Body

PHASE1CompletedINTERVENTIONAL
Enrollment

11

Participants

Timeline

Start Date

February 1, 2021

Primary Completion Date

March 25, 2021

Study Completion Date

March 25, 2021

Conditions
Healthy Volunteers (Intended Indication: Metastatic Patients With Triple Negative or HR+ Breast Cancer, or Hormone Sensitive Prostate Cancer)
Interventions
DRUG

Capivasertib

Subects will be administered single doses of capiversatib on Day 1 and Day 6.

DRUG

Itraconazole

Subjects will be administered itraconazole twice daily on Day 3, followed by once daily doses in the morning for 4 days.

Trial Locations (1)

14050

Research Site, Berlin

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Parexel

INDUSTRY

lead

AstraZeneca

INDUSTRY