A Drug Interaction Study of ACH-0145228

ACH-0145228 was dosed as 2 x 60 milligram (mg) (Part 1) or 1 x 40 mg (Part 2) powder in capsules.

Midazolam was dosed at 2 mg (1 milliliter \[mL\] of a 2 mg/mL syrup).

Digoxin was dosed as Lanoxin (or generic equivalent) at 1 x 0.25 mg tablet.

Itraconazole was dosed as Sporanox (or generic equivalent) at 200 mg (20 mL of a 10 mg/mL oral solution).