Southeast Asia Dose Optimization of Tafenoquine

PHASE4RecruitingINTERVENTIONAL
Enrollment

700

Participants

Timeline

Start Date

July 22, 2024

Primary Completion Date

October 4, 2027

Study Completion Date

February 7, 2028

Conditions
Plasmodium Vivax Malaria
Interventions
DRUG

Tafenoquine

Tafenoquine will be given as 100mg coated tablets. Tablets will be given based on weight bands.

DRUG

Chloroquine

Chloroquine will be given as daily dose over 3 days (25mg/kg total dose divided 10/10/5mg/kg)

DRUG

Artemether 20 mg-Lumefantrine 120 mg

Artemether-lumefantrine will be given twice daily over 3 days. Whole tablets will be given based on weight bands.

Trial Locations (5)

Unknown

NOT_YET_RECRUITING

Mahidol Oxford Tropical Medicine Research Unit (MORU), Cambodia, Siem Reap

RECRUITING

Lao Oxford Mahosot Hospital Wellcome Trust Research Unit (LOMWRU), Vientiane

NOT_YET_RECRUITING

Mahidol Vivax Research Unit (MVRU), Bangkok

NOT_YET_RECRUITING

Shoklo Malaria Research Unit (SMRU), Bangkok

NOT_YET_RECRUITING

Oxford University Clinical Research Unit (OUCRU), Bình Phước

All Listed Sponsors
lead

University of Oxford

OTHER