Substudy 02D: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Melanoma Brain Metastasis (MK-3475-02D/KEYMAKER-U02)

CHUV Centre Hospitalier Universitaire Vaudois ( Site 4602), Lausanne

Hôpitaux Universitaires de Genève (HUG)-Oncology ( Site 4603), Geneva

Melanoma Institute Australia ( Site 4402), Wollstonecraft

Sandton Oncology Medical Group (Pty) Ltd-Research ( Site 4863), Sandton

Calvary Mater Newcastle ( Site 4404), Waratah

CANCERCARE LANGENHOVEN DRIVE ONCOLOGY CENTRE ( Site 4865), Port Elizabeth

Cape Town Oncology Trials ( Site 4864), Cape Town

Universitaetsspital Zuerich ( Site 4601), Zurich

NYU Clinical Cancer Center ( Site 4002), New York

Hopital La Timone ( Site 4103), Marseille

Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 4399), Milan

Istituto Europeo di Oncologia ( Site 4301), Milan

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ( Site 4022), Baltimore

Inova Schar Cancer Institute ( Site 4011), Fairfax

Duke Cancer Institute ( Site 4005), Durham

Hospital Universitario Ramón y Cajal ( Site 4802), Madrid

Institut Claudius Regaud ( Site 4105), Toulouse

CHU de Bordeaux- Hopital Saint Andre ( Site 4108), Bordeaux

Istituto Oncologico Veneto IRCCS ( Site 4355), Padua

Martha Morehouse Tower ( Site 4020), Columbus

Policlinico Le Scotte - A.O. Senese ( Site 4377), Siena

Centre Hospitalier Lyon Sud ( Site 4102), Pierre-Bénite

A.P.H. Paris, Hopital Saint Louis ( Site 4107), Paris

University of Colorado, Anschutz Cancer Pavilion ( Site 4012), Aurora

Istituto Nazionale Tumori Fondazione Pascale ( Site 4302), Napoli

The Angeles Clinic and Research Institute ( Site 4009), Los Angeles

UCLA Hematology & Oncology ( Site 4004), Los Angeles

Providence Saint John's Health Center ( Site 4010), Santa Monica

Gustave Roussy ( Site 4101), Villejuif

HaEmek Medical Center ( Site 4703), Afula

Rambam Health Care Campus-Oncology ( Site 4704), Haifa

Rabin Medical Center-Oncology ( Site 4705), Petah Tikva

Chaim Sheba Medical Center ( Site 4701), Ramat Gan

Hadassah Ein Karem Jerusalem ( Site 4702), Jerusalem

LIFE GROENKLOOF-Mary Potter Cancer Centre ( Site 4861), Pretoria

HOSPITAL CLÍNIC DE BARCELONA-ICHMO- Clinic Institut of Haematological and Oncological diseases ( Site 4801), Barcelona