Absolute Bioavailability and ADME Study of [14C]AZD9977 in Healthy Male Subjects

PHASE1CompletedINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

December 21, 2020

Primary Completion Date

February 4, 2021

Study Completion Date

February 4, 2021

Conditions
Cardiovascular Disease
Interventions
DRUG

AZD9977 capsule 50 mg

100 mg dose of AZD9977 capsule 50 mg (as 2 x 50 mg capusles)

DRUG

[14C]AZD9977 Solution for Infusion, 20 µg/mL (NMT 37.0 kBq/5 mL)

One 100 µg dose of \[14C\]AZD9977 Solution for Infusion, 20 µg/mL (NMT 37.0 kBq/5 mL)

DRUG

[14C]AZD9977 Oral Suspension, 100 mg (NMT 9.9 MBq)

One 100 mg dose of \[14C\]AZD9977 Oral Suspension, 100 mg (NMT 9.9 MBq)

Trial Locations (1)

NG11 6JS

Research Site, Ruddington

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Quotient Sciences

INDUSTRY

lead

AstraZeneca

INDUSTRY