48
Participants
Start Date
December 22, 2021
Primary Completion Date
January 31, 2028
Study Completion Date
January 31, 2029
Dasatinib + Quercetin
D+Q will be administered once daily (1st dose of each cycle will be given, supervised, at the clinic visit; the 2nd dose will be taken at home) for 2 consecutive days followed by a 13-day (+/- 2 day) no-drug period for 12 consecutive weeks for 6 rounds of administration.
Placebo Capsules
Matching placebo capsules following the same administration protocol as the experimental treatment - administered once daily (1st dose of each cycle will be given, supervised, at the clinic visit; the 2nd dose will be taken at home) for 2 consecutive days followed by a 13-day (+/- 2 day) no-drug period for 12 consecutive weeks for 6 rounds of administration.
Wake Forest Health Sciences, Winston-Salem
Fundación ACE Clinical Site, Barcelona
Hospital Clínic de Barcelona Site, Barcelona
Sant Pau Clinical Site, Barcelona
FISEVI Clinical Site, Seville
The University of Texas Health Science Center at San Antonio
OTHER
Wake Forest University Health Sciences
OTHER
Washington University School of Medicine
OTHER