Study of Pelvic Hypofractionated Radiotherapy in Endometrial Cancer

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

January 15, 2021

Primary Completion Date

May 22, 2027

Study Completion Date

May 22, 2027

Conditions
Endometrial Cancer
Interventions
RADIATION

Hypofractionated Radiation

Radiation treatment in which the total dose of radiation is divided into large doses and treatments are given less often. Hypofractionated radiation therapy is given over a shorter period of time (fewer days or weeks) than standard radiation therapy.

OTHER

Clinical Follow-Up and Assessments

"At each visit, the subject will be evaluated for any signs of their endometrial cancer or symptoms returning (clinical disease recurrence) and any negative side effects associated with their prior radiation treatment. Study participants will also be asked to fill out a survey regarding bowel/urinary habits and quality of life questionnaires (known as the EPIC questionnaire) during these visits. The data collected during these clinical follow up visits will be used to determine how effective hypofractionated/shortened whole radiation therapy is for treating endometrial cancer."

Trial Locations (5)

30322

ACTIVE_NOT_RECRUITING

Winship Cancer Institute, Emory University, Atlanta

60612

RECRUITING

University of Illinois at Chicago (UIC), Chicago

60637

RECRUITING

University of Chicago, Chicago

77030

RECRUITING

MD Anderson Cancer Center, Houston

84112

RECRUITING

Huntsman Cancer Institute, Salt Lake City

All Listed Sponsors
lead

University of Chicago

OTHER