Plasma Resuscitation Without Lung Injury

PHASE4TerminatedINTERVENTIONAL
Enrollment

13

Participants

Timeline

Start Date

August 17, 2022

Primary Completion Date

June 29, 2024

Study Completion Date

September 29, 2024

Conditions
Burns
Interventions
DRUG

Pathogen-Reduced Plasma

The treatment group will receive an additional infusion of Pathogen-Reduced Plasma based on the formula, hourly rate, mL/hr = (1 mL\*kg\*TBSA)/24 hr. This infusion will not be titrated. It will be discontinued at the end of the 24th postburn hour.

DRUG

Crystalloid Solutions

The control group will receive an additional infusion of LR based on the formula: hourly rate, mL/hr = (1mL\*kg\*TBSA)/24 hr. this infusion will not be titrated. It will be discontinued at the end of the 24th postburn hour.

Trial Locations (6)

21201

University of Maryland School of Medicine, Baltimore

35294

University of Alabama at Birmingham Burn Center, Birmingham

37232

Vanderbilt University Medical Center, Nashville

77555

University of Texas Medical Branch, Galveston

78234-6315

U.S. Army Burn Center, Fort Sam Houston

98104-2499

University of Washington School of Medicine, Seattle

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Cerus Corporation

INDUSTRY

lead

Coalition for National Trauma Research

OTHER

NCT04681638 - Plasma Resuscitation Without Lung Injury | Biotech Hunter | Biotech Hunter